TARPγ2/4/8/Stargazin Monoclonal Antibody
Catalog No.: 11572 (clone S245-36)
Size: 100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
Stargazin belongs to a group of voltage- gated calcium channels that are present in most excitable cells. It appears to stabilize calcium channels in an inactivated (closed) state. Voltage-gated calcium channels exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival.
Antigen: Fusion protein corresponding to aa 203-323 (cytoplasmic C-terminus) of rat TARPγ2 (accession no. Q71RJ2).
Host Species: Mouse
Antibody Class: IgG2a
This antibody recognizes mouse and rat TARPγ2, TARPγ4, and TARPγ8. It does not cross-react with TARPγ3
Immunoblotting: use at 1ug/ml. Predicted molecular weight is 35-55kDa.
Positive control: Rat brain lysate.
These are recommended concentrations. User should determine optimal concentrations for their application.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid repeated freezing and thawing.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.