Anti-Quinidine Mouse Monoclonal Antibody – Library Pack (165101)

$632.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 5 x 100ug ELISA Quinidine
SKU: 165101 Categories: , , ,
Overview
Product Name Anti-Quinidine Mouse Monoclonal Antibody - Library Pack (165101)
Description Anti-Quinidine Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies:

16501 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD11-228.6.5 - Isotype IgG2b

16502 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD11-261.3.6 - Isotype IgG1

16503 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD11-265.2.3 - Isotype IgG1

16504 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD13-406.6.1 - Isotype IgG1

16505 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD14-504.5 - Isotype IgG1

Target Quinidine
Species Reactivity Quinidine
Applications ELISA
Host Mouse
Clonality Monoclonal
Immunogen Quinidine conjugated to KLH.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by Protein G affinity chromatography
Specificity Information
Specificity These antibodies recognize quinidine.
Target ID Quinidine
CAS Number 56-54-2
PubChem ID 441074
Research Areas Drugs
Background Quinidine is a class I antiarrhythmic agent. Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (INa) which causes the phase 0 depolarization of the cardiac action potential to decrease (decreased Vmax). Quinidine also blocks the slowly inactivating, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na /K -ATPase by binding to the same receptor sites as the digitalis glycosides such as ouabain.
Application Images
Description Quinidine is a class I antiarrhythmic agent.
Additional Information
Handling
Storage These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions These antibodies have been qualified for use in ELISA to detect quinidine.
References & Data Sheet