Neuroligin-4

Neuroligin-4 Monoclonal Antibody

ORDERING INFORMATION

Catalog no.: 56553 (clone S98-7)
Size: 100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.

BACKGROUND

Neuroligin-4 is a neuronal cell surface protein and a member of the type-B carboxylesterase- lipase protein family. Members of this family may act as splice site-specific ligands for beta- neurexins and may be involved in the formation and remodeling of central nervous system synapses. Neuroligin-4 interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.

SPECIFICATION SUMMARY

Antigen: Fusion protein corresponding to aa 782-945 (intracellular C-terminus) of mouse Neuroligin-4.
Accession nos.: ABS19580, B0F2B4
Gene Id: 100113365
Host Species: Mouse
Antibody Class: IgG1
Specificity: This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins.

APPLICATIONS

Immunoblotting: use at 1-2ug/ml. A band of ~125-130kDa is detected.
Immunofluorescence: use at 10ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their application.

DILUTION INSTRUCTIONS

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE AND STABILITY

This product is stable for at least one (1) year at -20°C.

For in vitro investigational use only. Not intended for therapeutic or diagnostic procedures.

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