IL-21 (IN) Polyclonal Antibody
Catalog No.: 41008
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Antigen: Peptide corresponding to aa 121-135 of human IL-21 precursor.
Host Species: Rabbit
Preservatives: 0.02% sodium azide
This antibody recognizes human IL-21, a cytokine that has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21, IL-21R, complexes with the common cytokine receptor γ chain, γc, and mediates IL-21 signaling. IL-21 and its receptor activate the JAK-STAT signaling pathway. IL-21 is expressed in activated T cells and the HL-60 and THP-1 cell lines. IL-21 is associated with the proliferation and maturation of NK, B and T cell populations.
Immunoblotting: use at 0.5-1 ug/ml. In immunoblots, a band of 18 kD is detected.
Positive control: HL60 or THP-1 cell lysates.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.