HEV (Hepatitis E Virus) IgM / recomWell
SKU: 5005 Categories: Infectious Disease Test Kits and Positive Controls, MIKROGEN Products
Product Name recomWell HEV IgM ELISA Kit (5005)
Description Enzyme immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgM antibodies against hepatitis E Virus (HEV) in human serum or plasma.
Target HEV IgM
Product Background Hepatitis E virus (HEV) is one of the leading causes of faecal-orally acquired hepatitis worldwide, usually resulting from contaminated drinking water. In developed countries, hepatitis E is usually transmitted through infected pork, which was not sufficiently cooked. HEV can be transmitted through blood products, blood transfusions and organ donation. In Europe most cases of hepatitis E are caused by the HEV genotype 3.The HEV infection usually remains symptomatic. Acute hepatitis E is an illness with a clinical presentation comparable to hepatitis A. Typical signs of hepatitis E include flu-like symptoms, vomiting, diarrhoea, fever, arthralgia and headache usually associated with a rise in liver enzyme values. Cholestatic jaundice that develops during the course of disease can persist for several weeks. HEV infection is usually self-limiting. In endemic regions in a high percentage of cases HEV infections during pregnancy follow a fulminant course, accompanied by a high mortality rate of approx. 20%. In males and non-pregnant females the mortality rate is 0.5% - 4.0%.For the recomWell HEV IgG, IgM purified recombinant antigens of the HEV genotypes 1 and 3 are used, thus guaranteeing reproducibly high sensitivity and specificity. The other HEV-genotypes 2 and 4 can be diagnosed by crossreactivity. The recomWell HEV IgG, IgM is highly suitable as a screening assay, especially in case of negative resulting hepatitis A-C-screening assay findings.
Species Reactivity Hepatitis E virus
Additional Information Additional Mirkogen Kit Information
Associated Products recomWell HEV IgG ELISA Kit (5004)
Target ID HEV IgM
Research Areas Infectious Disease
|10X Wash Buffer||100 mL|
|Dilution Buffer||125 mL|
|TMB Substrate||12 mL|
|Stop Slution||12 mL|
|Instuctions for Use||1 Each|
|Evaluation Form||1 Each|
|Microplate Sealing Tape||2 Each|
|Microtiter Plate||12 x 8 Wells|
|Positive Control||450 uL|
|Cut-Off Control||450 uL|
|Negative Control||450 uL|
|Anti-Human IgM Conjugate||500 uL|
Storage Store at 2 - 8ºC. Do not Freeze.