Heme Oxygenase 2 (HO-2) Polyclonal Antibody
Catalog No.: 13063
Format: 100ug (1mg/ml) Protein A-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Heme oxygenase (HO) catalyzes the degradation of heme at the alpha-methene bridge to form biliverdin. Three isoforms of heme oxygenase are known. Heme oxygenase 1 (HO-1) is an inducible isoform in response to stress such as oxidative stress, hypoxia, heavy metals, cytokines, etc. Heme oxygenase 2 (HO-2) is a constitutive isoform that is expressed under homeostatic conditions. Both HO-1 and HO-2 are ubiquitously expressed and catalytically active. HO-1 is encoded by the HMOX1 gene and HO-2 by HMOX2. A third heme oxygenase (HO-3) is not catalytically active, but is thought to work in oxygen sensing.
Antigen: Full-length native rat HO-2 purified from testes.
Accession no.: NP_077363.1, P23711
Gene ID: 79239
Host Species: Rabbit
Specificity: This antibody recognizes human, mouse, and rat HO-2.
Immunoblotting: use at 1ug/ml.
Immunohistochemistsry: use at 1ug/ml.
These are recommended concentrations. Endusers should determine optimal concentrations for their applications.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C.
For in vitro investigational use only. Not intended for diagnostic or therapeutic applications.