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Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody – Library Pack

$506.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 4 x 100ug ELISA,IHC,RIA,IF Human
SKU: 193101 Categories: , , ,
Overview
Product Name Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Library Pack (193101)
Description Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies:

19301 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-327.8 - Isotype IgG1
19302 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-372.14 - Isotype IgG1
19303 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-387.5 - Isotype IgG1
19304 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-426.12 - Isotype IgG1
Target Gonadotropin Releasing Hormone
Species Reactivity Human
Applications ELISA,IHC,RIA,IF
Host Mouse
Clonality Monoclonal
Immunogen Purified human gonadotropin releasing hormone.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by protein G affinity chromatography
Specificity Information
Specificity These antibodies recognize human GnRH.
Target ID Gonadotropin Releasing Hormone
Research Areas Hormones/Proteins
Background Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH), is a 10 amino acid neurohormone produced in the hypothalamus. GnRH stimulates the synthesis and secretion of the two gonadotropins—luteinizing hormone (LH) and follicle- stimulating hormone (FSH)—by the anterior pituitary gland. Characteristic of all releasing hormones, and most striking in the case of GnRH, is the phenomenon of pulsatile secretion. Under normal circumstances, GnRH is released in pulses at intervals of about 90 to 120 minutes. Abnormalities in the pulsatile secretion of GnRH result in subnormal fertility and abnormal or absent menstruation. Constant administration of GnRH suppresses gonadotropin secretion, which has therapeutic benefits in certain patients, such as children with precocious puberty and men with prostate cancer.
Application Images
Description RIA
Description Immunofluorescent detection of mouse GnRH neuronal cells with #19304 (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Additional Information
Handling
Storage Store at 2 - 8°C. Do not Freeze.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions These antibodies have been qualified for use in ELISA, immunohistochemistry, and RIA to detect human GnRH.

Endusers should determine optimal concentrations for their applications.RIA
References & Data Sheet