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Anti-GLUT10 Antibody (28103)

$384.00

Host Quantity Applications Species Reactivity Data Sheet  
Rabbit 100ug WB Human
SKU: 28103 Categories: , ,
Overview
Product Name Anti-GLUT10 Antibody (28103)
Description Anti-GLUT10 Rabbit Polyclonal Antibody
Target GLUT10
Species Reactivity Human
Applications WB
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acids 367-385 (ILSTAKKTKPHPRSGDPSA) of human GLUT10 conjugated to KLH at the N- terminus.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by peptide immuno-affinity chromatography
Specificity Information
Specificity This antibody recognizes human GLUT10.
Target Name Solute carrier family 2, facilitated glucose transporter member 10
Target ID GLUT10
Uniprot ID O95528
Alternative Names Glucose transporter type 10, GLUT-10
Gene Name SLC2A10
Sequence Location Endomembrane system, Cytoplasm, perinuclear region
Biological Function Facilitative glucose transporter required for the development of the cardiovascular system. {PubMed:11592815, PubMed:16550171}.
Research Areas Neuroscience
Background Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetic causes. Genome-wide screening has identified several susceptibility loci for NIDDM within the human genome. Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUT or SLC2A family). The gene for GLUT10, localized to human chromosome 20q12-q13.1, is a candidate gene for NIDDM susceptibility. It is widely expressed, with highest levels in liver and pancreas.
Application Images
Additional Information
Handling
Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected.

Positive control: transfected cell lysate
References & Data Sheet
References Wood,IS, Hunter,L and Trayhurn,P (2003) Biochem Biophys Res Commun 308: 43-49.
McVie-Wylie,AJ, Lamson,DR and Chen,YT (2001) Genomics 72: 113-117.