Catalog No.: 28103
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma- tography.
Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetic causes. Genome-wide screening has identified several susceptibility loci for NIDDM within the human genome. Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUT or SLC2A family). The gene for GLUT10, localized to human chromosome 20q12-q13.1, is a candidate gene for NIDDM susceptibility. It is widely expressed, with highest levels in liver and pancreas.
Immunogen: Synthetic peptide corresponding to amino acids 367-385 (ILSTAKKTKPHPRSGDPSA) of human GLUT10 conjugated to KLH at the N- terminus.
Host Species: Rabbit
Preservatives: None. Available on request.
This antibody recognizes human GLUT10.
Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected.
Positive control: transfected cell lysate
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY5h>
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Wood,IS, Hunter,L and Trayhurn,P (2003) Biochem Biophys Res Commun 308: 43-49.
McVie-Wylie,AJ, Lamson,DR and Chen,YT (2001) Genomics 72: 113-117.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.