Fibroblast Growth Factor Receptor 1 (FGFR1)

FGF Receptor 1 Monoclonal Antibodies

ORDERING INFORMATION

Catalog No.: 30103 (M17D10)
Size: 250 ug Protein G-purified antibody in PBS, pH 7.4

SPECIFICATION SUMMARY

Antigen: Recombinant human ectodomain of FGFr1β expressed in E. coli from pro23 to his415; antigen contained NH2-terminal gly-ser-pro-gly- ile and COOH-terminal glu-phe sequences.
Host Species: Mouse
Antibody Class: IgG1
Stabilizers: None
Preservatives: None. Available on request.

SPECIFICITY

30103 reacts with both α and β isoforms. Epitope is within the sequence pro179 to lys195 in Ig loop II.

APPLICATIONS

Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo- viral, or native FGFr1.
Immunoprecipitation: native, recombinant, and ligand-labeled FGFr1. Immunohistochemistry: under investigation.

DILUTION INSTRUCTIONS

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE AND STABILITY

These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

REFERENCES

Xu et al. (1992) J Biol Chem 267: 1779;
Robinson et al. (1995) Development 121: 3959.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.

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