Catalog No.: 34022
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma- tography.
The novel peptide sequence SSKKQKRSHK within BRCAA1 protein was mapped to the cytoplasm of MCF-7 cells. Immunohistochemical analysis demonstrated that this sequence was expressed in 65% of breast tumors. Its expression may be useful in diagnosis and prognosis of breast cancer.
Immunogen: Synthetic peptide corresponding to amino acids 1046- 1055 (SSKKQKRSHK) of human BRCAA1 conjugated to KLH.
Host Species: Rabbit
Preservatives: None. Available on request.
This antibody recognizes human, mouse, and rat BRCAA1.
Immunoblotting : use at 1:500-1:1,000 dilution. A band of approximately 136 kDa is detected.
Positive control: MCF-7 human breast cancer cell lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Cui, D et al. (2004) Cancer Epidemiol Biomarkers Pres 13: 1136-45.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.