Anti-APRIL (ED) Antibody

$455.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	ELISA,WB	Human, Drosophila

SKU: 41000 Categories: Antibody Products, Growth Factors/Cytokines/Receptor Antibodies, Products

Overview

Product Name Anti-APRIL (ED) Antibody (41000)

Description Anti-APRIL (ED) Rabbit Polyclonal Antibody

Target APRIL (ED)

Species Reactivity Human, Drosophila

Applications ELISA,WB

Host Rabbit

Clonality Polyclonal

Immunogen Peptide corresponding to aa 50-100 of human APRIL.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, 0.02% sodium azide.

Buffer Formulation Phosphate Buffered Saline

Buffer Anti-Microbial 0.02% Sodium Azide

Format Purified

Purification Purified by Protein A affinity chromatography

Specificity Human APRIL. Reactivity with other species has not been investigated.

Target Name Tumor necrosis factor ligand superfamily member 13

Target ID APRIL (ED)

Uniprot ID O75888

Alternative Names A proliferation-inducing ligand, APRIL, TNF- and APOL-related leukocyte expressed ligand 2, TALL-2, TNF-related death ligand 1, TRDL-1, CD antigen CD256

Gene Name TNFSF13

Sequence Location Secreted

Biological Function Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. {PubMed:10973284}.

Research Areas Growth Factors, Cytokines, Receptors

Background APRIL (A Proliferation-Inducing Ligand) is a member of the TNF superfamily identified in human and mouse. Two receptors for APRIL have been designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its receptors BCMA and TACI are involved in autoimmunity and cancer.