Specificity Any 18750: G1 virus attachment glycoprotein (120 kD); virus-neutralizing. 18752: G2 envelope glycoprotein (35kD); virus-neutralizing.18754: G2 envelope glycoprotein (35 kD); virus-neutralizing.18756: rec 30101 reacts with both alpha and b isoforms. Epitope is within the NH2-terminus of Ig loop II sequence lys145 and glu159 between the acidic box and heparin-binding sequence of FGFr1. 30103 reacts with both alpha and b isoforms. Epitope is within the sequence pro179 to lys195 in Ig loop II. 30104 reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1alpha. Reacts with human, rat, and mouse receptor. Other spe 30105 reacts with the COOH-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu75 and ser119 of FGFr1alpha. Epitope is masked in undenatured FGFr1alpha. 30106 reacts with the b isoform of FGFr1. Epitope is undetermined but presumed to be near junction of the common FGFr1 NH2-terminus and NH2- terminus of Ig loop II. All four clones recognize human insulin receptor; low-level cross-reactivity with bovine and rabbit insulin receptor. Antibody was affinity-purified on GST. Antibody was affinity-purified on the peptide. Antibody was affinity-purified on the peptide. This antibody does not recognize all N-terminal 6-His tagged proteins. Detects 90kDa Hsp90b in all reactive species except chicken where it detects both alpha and beta isoforms. Recombinant rat PSD95 Recombinant retinoblastoma These antibodies specifically recognize human TS (36 kDa). They do not cross-react with rat TS. This affinity-purified antibody reacts with human, mouse, rat and bovine AMPK alpha-2. The epitope recognized is in the region between aa 350 and 400 of AMPK alpha-2. Based on 100% sequence identity, This antibody detects 72 and 73kDa proteins corresponding to the predicted molecular masses of Hsp70 and Hsc70, respectively, on immunoblots of human, mouse, rat, rabbit, monkey, hamster, guinea pig, This antibody detects a 23kDa protein in human (and a 19kDa protein in other species) on SDS-PAGE immunoblots, corresponding to the molecular mass of Cu/Zn SOD. This antibody recognizes human, mouse, This antibody detects a 23kDa protein in human (and a19 kDa protein in other species) on SDS-PAGE immunoblots, corresponding to the molecular mass of Cu/Zn SOD. This antibody recognizes human, mouse, This antibody detects a 25kDa protein on SDS-PAGE immunoblots corresponding to the molecular mass of Mn SOD. This antibody recognizes human, monkey, mouse, rat, bovine, canine, porcine, hamster, gerb This antibody detects a 25kDa protein on SDS-PAGE immunoblots corresponding to the molecular mass of Mn SOD. This antibody recognizes human, monkey, mouse, rat, bovine, canine, porcine, hamster, guin This antibody reacts with both alpha (denatured) and b isoforms. Epitope is within the sequence his241 and val267 between Ig loops II and III. Epitope is masked in undenatured FGFr1alpha. This antibody reacts with GMP-140 (P- selectin) on activated human platelets; it does not react with resting platelets. It does not interfere with platelet aggregation or platelet adhesion. It does n This antibody reacts with human and mouse. Antibody is affinity purified. This antibody reacts with human and rat. Antibody is affinity purified. This antibody reacts with human Aurora kinase A, and the epitope recognized maps to a region between residues 50-100 of human Aurora kinase A. Based on 100% sequence identity this antibody is predict This antibody reacts with human Aurora kinase A, and the epitope recognized maps to a region between residues 75-125 of human Aurora kinase A. Based on 100% sequence identity this antibody is predict This antibody reacts with human BRD2.The specific epitope is in the region between aa 550 and 600 of human BRD2.Based on 100% sequence identity, this antibody is predicted to react with Bovine, Rhesu This antibody reacts with human, mouse and rat. Antibody is affinity purified. This antibody reacts with human, mouse, rat and bovine AMP activated protein kinase, alpha-1 catalytic subunit. Based on 100% sequence identity, this antibody is predicted to react with Chicken, Turk This antibody reacts with human. Other species have not been tested. Antibody is affinity purified. This antibody reacts with phosphotyrosine and detects phosphotyrosine in proteins of unstimulated and stimulated cell lysates. It does not cross-react with phosphoserine or phosphothreonine. This antibody recognizes 3-nitrotyrosine moieties, species-independent. No detectable reactivity with non-nitrated tyrosine. This antibody recognizes a peptide backbone epitope that is common to all types of amyloid oligomers but is not found in native proteins, amyloidogenic monomers, or mature amyloid fibrils. This antibody recognizes Ab1-16 as well as other Ab peptides: Ab37, Ab38, Ab39, Ab40, and Ab42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition and to older mice with higher A This antibody recognizes an ~85 kDa protein (inactive form) in unstressed cell lysates and an ~95 kDa protein (active form) in heat-shocked cell lysates of human, mouse, rat, rabbit, bovine, guinea p This antibody recognizes an ~98 kDa protein corresponding to the predicted molecular mass of Grp94 on SDS-PAGE immunoblots in human, mouse, rat, rabbit, monkey, hamster, guinea pig, dog, bovine, shee This antibody recognizes an 84 kD nuclear matrix protein that was first discovered through its association with the N-terminal region of retinoblastoma protein. This antibody recognizes an epitope within aa 223-322 of human E2F-1. This antibody recognizes an epitope within aa 244-264 of human E2F-1. This antibody recognizes an epitope within aa 332-390 of human E2F-1. This antibody recognizes an epitope within Ab1-16 as well as other Ab peptides: Ab37, Ab38, Ab39, Ab40, and Ab42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition and to older This antibody recognizes an epitope within amino acid residues 1-20 of human, mouse and rat TBP. It does not react with TBP from Drosophila, yeast, silk worm, or Xenopus. Other species not investigat This antibody recognizes DMPO, DMPO-octanoic acid, DMPO-protein adducts, and DMPO-DNA adducts. It does not cross-react with non-adducted proteins or DNA. Species independent. This antibody recognizes epitopes common to many human amyloid fibrils and fibrillar oligomers but not prefibrillar oligomers or natively folded proteins. Predicted to recognize mouse and rat based o This antibody recognizes eukaryotic Hsp90alphab. This antibody recognizes full-length ATM, a 370 kD nuclear phosphoprotein, which is involved in the autooal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins ass This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the deltaexon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness This antibody recognizes full-length human caspase-9 (46kDa). This antibody recognizes full-length human CXCR4 (40 kD). This antibody recognizes full-length human IRAK (80 kD). This antibody recognizes full-length human, monkey, and mouse Daxx (120kDa). This antibody recognizes full-length STAT1alpha (91 kD) and does not react with STAT1b. This antibody recognizes GST. This antibody recognizes human and bovine Annexin 1. This antibody recognizes human and mouse ch-TOG. A BLAST search demonstrated 100% identity to the peptide immunogen in human, mouse, rat, chimpanzee, dog, cow, chicken, opossum, and frog. This antibody recognizes human and mouse Id3. This antibody recognizes human and mouse JAB-1. This antibody recognizes human and mouse MyD88 (35 kD). This antibody recognizes human and mouse RbAp48 and RbAp46. This antibody recognizes human and mouse RbAp48. This antibody recognizes human and mouse RPA14. RPA (Replication Protein A) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32, and 14 kD. T This antibody recognizes human and mouse RPA32. RPA (Replication Protein A) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32, and 14 kD. T This antibody recognizes human and rabbit ER-alpha, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-alpha is a ligand-activated transcription factor that, when bound to es This antibody recognizes human CD74. This antibody recognizes human Cdc34. This antibody recognizes human DNA Ligase I (125 kD), one of the four ligase proteins found in mammalian cells that are required for the joining of DNA strand breaks that occur during DNA replication This antibody recognizes human EAAC1. This antibody recognizes human EndoPDI. This antibody recognizes human FEN-1. This antibody recognizes human Hsp27. This antibody recognizes human p38alpha MAPK. This antibody recognizes human Rad50, a 153 kD protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex. Following DNA damage This antibody recognizes human Rad51, a 37 kD protein that interacts with BRCA1. This interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact via the BRC repe This antibody recognizes human SMRT. This antibody recognizes human Trip230, a 230 kD protein. The gene for Trip230 is located on chromosome 14q31 in a region associated with genetic alterations and thyroid hormone response abnormalitie This antibody recognizes human, monkey, mouse, and rat SRC-1. This antibody recognizes human, monkey, mouse, rat, hamster, bovine, ovine, porcine, canine, guinea pig, and Xenopus PDI. This antibody recognizes human, mouse (weak), and rat Shank2. It does not cross- react with Shank1 or Shank3. This antibody recognizes human, mouse and rat GIT1. It does not cross-react with GIT2. This antibody recognizes human, mouse and rat KCC2. This antibody recognizes human, mouse and rat KCNQ1. This antibody recognizes human, mouse and rat KCNQ4. This antibody recognizes human, mouse, and chicken DNA Ligase III. Cellular localization is nuclear and mitochondrial. This antibody recognizes human, mouse, and rabbit LAMP2 (~100-110 kDa).Accession no.: NP_001017959.1 Gene ID: 16784 This antibody recognizes human, mouse, and rat Ataxin-1. This antibody recognizes human, mouse, and rat Cav3.2. It does not cross-react with Cav1.3. This antibody recognizes human, mouse, and rat Cavb2. It does not cross-react with Cav b1, Cav b3, or Cav b4. This antibody recognizes human, mouse, and rat Copper-Transporting ATPase1.Immunohistochemistry: use at 1-5ug/ml. These are recommended concentrations.Enduser should determine optimal concentrations This antibody recognizes human, mouse, and rat Copper-Transporting ATPase2. This antibody recognizes human, mouse, and rat Hsc70. Other species have not been tested. It does not cross-react with Hsp70. This antibody recognizes human, mouse, and rat Hsp40 (Hdj1). Other species have not been tested. It does not cross-react with Hdj2 or Ydj1. This antibody recognizes human, mouse, and rat Hsp90alpha and b. Other species have not been tested. This antibody recognizes human, mouse, and rat Hsp90alpha. Other species have not been tested. It does not cross-react with Hsp90b in ELISA. This antibody recognizes human, mouse, and rat mGluR1 and mGluR5. This antibody recognizes human, mouse, and rat mGluR1/5. This antibody recognizes human, mouse, and rat MMP 9. This antibody recognizes human, mouse, and rat Mre11. This antibody recognizes human, mouse, and rat Nav1.7. It does not cross-react with other Nav channels. This antibody recognizes human, mouse, and rat Shank 1, 2, and 3. This antibody recognizes human, mouse, and rat Shank3. It does not cross-react with Shank1 or Shank2. This antibody recognizes human, mouse, and rat Smac (25kDa). This antibody recognizes human, mouse, and rat TrpC5. This antibody recognizes human, mouse, and rat TrpC7. This antibody recognizes human, mouse, and rat TrpV3. This antibody recognizes human, mouse, fish, rat, avian, amphibian, Drosophila, and yeast Hsp70, Hsc70, and, following heat shock, Hsp72. This antibody recognizes human, mouse, rat, beluga, bovine, canine, fish, guinea pig, hamster, monkey, porcine, ovine, and coral Hsp70. This antibody recognizes human, mouse, rat, bovine, canine, guinea pig, and hamster Hsp 25/27. Some cross- reactivity with alpha B crystallin. This antibody recognizes human, mouse, rat, bovine, chicken, dog, guinea pig, hamster, pig, monkey, rabbit, and sheep p38. This antibody recognizes human, mouse, rat, dog, and hamster FKBP52. This antibody recognizes human, mouse, rat, fish, avian, amphibian, Drosophila, and yeast Hsp70, Hsc70, p75, and, following heat shock, Hsp72. This antibody recognizes human, mouse, rat, fish, avian, rabbit, amphibian, Drosophila, and yeast Hsp70, Hsc70, Grp78, and, following heat shock, Hsp72. This antibody recognizes human, mouse, rat, hamster, and monkey TSG101 protein. This antibody recognizes human, mouse, rat, rabbit, bovine, canine, porcine, ovine, guinea pig, hamster, chicken, monkey, Xenopus, and Drosophila Hsp60 (60 kDa). It does not cross-react with bacteria This antibody recognizes human, mouse, rat, rabbit, bovine, porcine, and chicken Hsp90alpha (90 kDa). This antibody recognizes human, rat, and hamster LAMP1.Accession no.: NP_036989.1 Gene ID: 25328 This antibody recognizes human, rat, and squirrel monkey SgII. This antibody recognizes inducible and constitutive Hsp70/Hsc70 of human, mouse, rat, rabbit, monkey, guinea pig, hamster, chicken, bovine, canine, ovine, porcine, fish, Xenopus, Drosophila, C. elega This antibody recognizes mitosin, a 350 kD phosphoprotein that is specifically involved in mitotic-phase progression. Mitosin is expressed throughout S, G2, and M phases of the cell cycle, but is abs This antibody recognizes mouse and rat RIP3 (57kDa). This antibody recognizes non-cleaved (45kDa) and cleaved DFF45. This antibody recognizes proteins containing acetylated lysine residues. It does not react with non-acetylated lysine residues. This antibody recognizes proteins containing acetylated lysine residues. It does not recognize non-acetylated proteins. This antibody recognizes proteins containing methylated lysine residues. It does not recognize non-methylated proteins. This antibody recognizes ski protein of human, mouse, rat, chicken, and Xenopus. This antibody recognizes the 95 kD nibrin protein which contains a forkhead-associated domain that is adjacent to BRCT, a breast cancer C- terminal domain involved in protein- protein interactions. p This antibody recognizes the C-terminal aa TETSQVAPA(COOH) of native and recombinant vertebrate rhodopsin. This antibody recognizes the fiber knob protein of human adenovirus 3. The fiber knob is involved in the initial interaction of adenovirus with cellular membrane receptors. This antibody recognizes the N-terminus of Rhodopsin from all mammalian species tested (human, mouse, rat, bovine, porcine), and most fish, birds, and amphibians. This antibody recognizes the phosphorylated and non-phosphorylated forms of mouse, rat, and bovine CaMKII. This antibody recognizes the phosphorylated form of mouse and rat CaMKII. It does not react with non- phosphorylated CaMKII. This antibody recognizes yeast Hsp40 (Ydj1). It does not cross-react with human, mouse, or rat Hsp40. This antibody specifically recognizes an epitope within Abx-40. NOTE: When administered to young Tg2576 mice with minimal Ab deposition, this antibody reduced Ab accumulation in the brain. This antibody specifically recognizes an epitope within Abx-42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition, this antibody reduced Ab accumulation in the brain. All three clones are specific for the human IGF-1 receptor; 35102 and 35103 recognize the alpha subunit: 35101 (3B7) stimulates binding of IGF-1 and -2; stimulates basal and IGF- 1 stimulated cell gr
