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Anti-P-Cadherin Antibody (42028)

$484.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ug WB,IHC,Inhibition Human
SKU: 42028 Categories: , ,
Overview
Product Name Anti-P-Cadherin Antibody (42028)
Description Anti-Human P-cadherin Mouse Monoclonal Antibody
Target P-Cadherin
Species Reactivity Human
Applications WB,IHC,Inhibition
Host Mouse
Clonality Monoclonal
Clone ID NCC-CAD-299
Isotype IgG1
Immunogen Human epidermal carcinoma cell line A431.
Properties
Form Lyophilized
Formulation 10 mM PBS, pH 7.4, lyophilized
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity This antibody specifically reacts with human P-Cadherin, and inhibits P- Cadherin dependent cell-cell contact.
Target Name Cadherin-3
Target ID P-Cadherin
Uniprot ID P22223
Alternative Names Placental cadherin, P-cadherin
Gene Name CDH3
Sequence Location Cell membrane; Single-pass type I membrane protein.
Biological Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Research Areas Cell adhesion
Application Images
Additional Information
Handling
Storage Lyophilized antibody is stable at 4°C for 2 years. Store the reconstituted solution in aliquots at -20°C for one year or at 4°C for 6 months after addition of 0.1% sodium azide by the user. Avoid repeated freeze-thaw cycles.
Dilution Instructions Reconstitute in distilled water to the final desired concentration.
Application Instructions Western Blotting: 5-10 ug/ml, non-reducing and non-heating conditions.

Immunohistochemistry: 5-10 ug/ml, frozen tissue sections.

Cell Contact Inhibition Assays: 100 ug/ml
References & Data Sheet