Anti-FBG3 Antibody (28104)
$384.00
| Host | Quantity | Applications | Species Reactivity | Data Sheet | |
|---|---|---|---|---|---|
| Rabbit | 100ug | WB,ELISA | Human |  |
Overview
Product Name Anti-FBG3 Antibody (28104)
Description Anti-FBG3 (F Box 3) Rabbit Polyclonal Antibody
Target FBG3
Species Reactivity Human
Applications WB,ELISA
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acids 103-119 (EWKVEDLSRDQRKEFPN) of human
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by peptide immuno-affinity chromatography
Specificity Information
Specificity This antibody recognizes human FBG3 . Sequence homology to mouse and rat FBG3 is 94%.
Target Name F-box only protein 44
Target ID FBG3
Uniprot ID Q9H4M3
Alternative Names F-box protein FBX30, F-box/G-domain protein 3
Gene Name FBXO44
Biological Function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Research Areas Neuroscience
Background F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F- box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
Handling
Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions Immunoblotting : use at 1:500 dilution. A band of approximately 31 kDa is detected.
Positive control: recombinant human FBG3.
Positive control: recombinant human FBG3.
Download PDF Data Sheet