Specificity Any 56203, 56204, and 56205 recognize S-100alphab and S-100 bb. 56206 recognizes S-100alphab. Peptide corresponding to aa 653- 662 of human amyloid protein precursor (APP) or aa 1-10 of the 4kD Ab peptide generated by b- and g-secretases. The sequences are identical to those of rabbit, pig, c These antibodies react specifically with CRF. There is no cross-reactivity with bovine serum albumin, insulin, ovalbumin, or epidermal growth factor. These two antibodies recognize different epitopes This antibody detects lead in the ppb range. Indirect ELISA endpoint titer is >1: 100,000. This antibody detects wild-type transfected, endogenous, or GST- SAP30L fusion protein in human cell lines. This antibody reacts specifically with cyclic GMP. This antibody reacts with bovine and porcine S100A1 in immunoblots. Immunoreactivity with recombinant rat and human S100A1 and recombinant human S100A4 is reduced when compared to native bovine and p This antibody reacts with human and Dictyostelium discoideum calnexin. This antibody reacts with phosphotyrosine and detects phosphotyrosine in proteins of unstimulated and stimulated cell lysates. It does not cross-react with phosphoserine or phosphothreonine. This antibody reacts with rat EAAT1 protein. Cross-reactivity with human and mouse EAAT1 is predicted based on sequence homology. This antibody reacts with residues 130-136 in human myelin basic protein (21.5kDa and 18.5kDa molecular forms). It also recognizes primate, rabbit, sheep, goat, rat, and mouse myelin basic protein. This antibody recognizes 3-nitrotyrosine moieties, species-independent. No detectable reactivity with non-nitrated tyrosine. This antibody recognizes a peptide backbone epitope that is common to all types of amyloid oligomers but is not found in native proteins, amyloidogenic monomers, or mature amyloid fibrils. This antibody recognizes Ab1-16 as well as other Ab peptides: Ab37, Ab38, Ab39, Ab40, and Ab42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition and to older mice with higher A This antibody recognizes amino acids human FBG4. Sequence homology to mouse and rat FBG4 protein is 100%. This antibody recognizes an epitope at the C-terminus of human CIKS/Act1 (Connection to IKK and SAPK/JNK), an activator of IKK. CIKS/Act1 interacts directly with IKKg and also activates activating tr This antibody recognizes an epitope at the C-terminus of human DUX4. It does not cross-react with DUX4c. This antibody recognizes an epitope at the C-terminus of human, mouse, and rat NAK/TBK1 (NF-kappaB Activating Kinase and TANK-Binding Kinase 1). NAK/TBK1 activates IKKb through direct phosphorylation This antibody recognizes an epitope at the N-terminus of human CIKS/Act1 (Connection to IKK and SAPK/JNK), an activator of IKK. CIKS/Act1 interacts directly with IKKg and also activates activating tr This antibody recognizes an epitope within Ab1-16 as well as other Ab peptides: Ab37, Ab38, Ab39, Ab40, and Ab42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition and to older This antibody recognizes epitopes common to many human amyloid fibrils and fibrillar oligomers but not prefibrillar oligomers or natively folded proteins. Predicted to recognize mouse and rat based o This antibody recognizes full-length human IRAK (80 kD). This antibody recognizes full-length human IRAK2 (65 kD). This antibody recognizes full-length STAT1alpha (91 kD) and does not react with STAT1b. This antibody recognizes human and mouse Alpha-2C adrenergic receptor. This antibody recognizes human and mouse BACE (approx. 70 kD). This antibody recognizes human and mouse BDNF. This antibody recognizes human and mouse choline acetyltransferase. This antibody recognizes human and mouse GABARAP. This antibody recognizes human and mouse Id3. This antibody recognizes human and mouse JAB-1. This antibody recognizes human and mouse MyD88 (35 kD). This antibody recognizes human and mouse PARK7 (DJ-1). Sequence homology to mouse and rat DJ-1 is 82%. This antibody recognizes human and mouse Tau. This antibody recognizes human and rat ATF4. This antibody recognizes human and rat GLUT2.. This antibody recognizes human and rat LRRK2. This antibody recognizes human and rat Piccolo isoforms (other species not yet tested). It does not cross-react with Bassoon. This antibody recognizes human BACE2 (approx. 75 kD). This antibody recognizes human beta-actin. This antibody recognizes human CD74. This antibody recognizes human Cdc34. This antibody recognizes human DENTT (Differentially Expressed Nucleolar TGF-b1 Target) protein, a gene product expressed in several normal tissues with the highest level of expression in brain. DENT This antibody recognizes human DPP10. This antibody recognizes human DUX4. It does not cross-react with DUX4c. This antibody recognizes human EAAC1. This antibody recognizes human EndoPDI. This antibody recognizes human FBG3 . Sequence homology to mouse and rat FBG3 is 94%. This antibody recognizes human FEN-1. This antibody recognizes human GABARAP (14 kD). This antibody recognizes human GABARAPL1. This antibody recognizes human GLUT10. This antibody recognizes human Humanin conjugated to carrier proteins, as free polypeptide, and as a fusion protein. This antibody recognizes human IKKalpha (85 kD). No cross-reactivity with IKKb or IKKg. This antibody recognizes human IKKalpha (85 kD). No cross-reactivity with IKKb or IKKg.<h5 This antibody recognizes human IKKb (87 kD). No cross-reactivity with IKKalpha or IKKg. This antibody recognizes human IKKepsilon (80 kD). No cross-reactivity with IKKalpha, IKKb or IKKg. This antibody recognizes human IL- 1RAcP (66 kD). No cross-reactivity with other members of the IL-1 receptor family. This antibody recognizes human IRAK2 (65 kD). No cross-reactivity with IRAK. This antibody recognizes human NIK. This antibody recognizes human NPFF1 (45 kD). This antibody recognizes human NPFF2 (45 kD). This antibody recognizes human otoferlin. This antibody recognizes human p38alpha MAPK. This antibody recognizes human p62dok (62kD). This antibody recognizes human PINK1. This antibody recognizes human PKD2. This antibody recognizes human SERPINB10 protein, a gene product that is expressed in human bone marrow cells. Members of the human serpin family regulate a diverse array of serine and cysteine prote This antibody recognizes human SERPINB13 protein, a gene product that is expressed in normal oral mucosa, skin, and cultured keratinocytes. It is underexpressed in oral squamous cell carcinomas. Memb This antibody recognizes human SIRP alpha 1, 2, and 3. This antibody recognizes human SMRT. This antibody recognizes human SOX6 and is predicted to recognize mouse, rat, and chimpanzee SOX6 based on 100% sequence homology. This antibody recognizes human, monkey, mouse, and rat SRC-1. This antibody recognizes human, monkey, mouse, rat, hamster, bovine, ovine, porcine, canine, guinea pig, and Xenopus PDI. This antibody recognizes human, mouse (weak), and rat Shank2. It does not cross- react with Shank1 or Shank3. This antibody recognizes human, mouse and rat AMIGO-1. It does not cross- react with AMIGO-2 or AMIGO-3. This antibody recognizes human, mouse and rat GFAP. It cross-reacts with GFAP- R416W and other GFAP mutant proteins. This antibody recognizes human, mouse and rat GIT1. It does not cross-react with GIT2. This antibody recognizes human, mouse and rat LRRK2. This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4. This antibody recognizes human, mouse and rat VDAC1. It does not cross-react with VDAC2 or VDAC3 (based on evaluation in knock-out mice). This antibody recognizes human, mouse, and rat Akirin1. This antibody recognizes human, mouse, and rat Alpha 1 GABA-A receptor. It does not cross-react with Alpha 2 or Alpha 3 GABA-A receptors. This antibody recognizes human, mouse, and rat Ankyrin-B. This antibody recognizes human, mouse, and rat Ankyrin-G. This antibody recognizes human, mouse, and rat APP and the C99 fragment. This antibody recognizes human, mouse, and rat Ataxin-1. This antibody recognizes human, mouse, and rat BACE2 (approx. 75 kD). This antibody recognizes human, mouse, and rat Bassoon. Multiple isoforms are detected. This antibody recognizes human, mouse, and rat Beta 3 GABA-A receptor. It does not cross-react with Beta 1 or 2 GABA-A receptor. This antibody recognizes human, mouse, and rat Copper-Transporting ATPase1.Immunohistochemistry: use at 1-5ug/ml. These are recommended concentrations.Enduser should determine optimal concentrations This antibody recognizes human, mouse, and rat Copper-Transporting ATPase2. This antibody recognizes human, mouse, and rat FBG2. This antibody recognizes human, mouse, and rat FBG5. This antibody recognizes human, mouse, and rat GABA(B)R1. It does not cross- react with GABA(B)R2. This antibody recognizes human, mouse, and rat GABA(B)R2. It does not cross- react with GABA(B)R1. This antibody recognizes human, mouse, and rat GFAP. This antibody recognizes human, mouse, and rat GFRalpha-1 (approx. 50 kD). This antibody recognizes human, mouse, and rat GFRalpha-2 (52 kD). This antibody recognizes human, mouse, and rat GFRalpha-3 (approx. 43 kD). This antibody recognizes human, mouse, and rat GluN2A/NR2A. It does not cross- react with NR2B. This antibody recognizes human, mouse, and rat IKKg (52 kD). No cross-reactivity with IKKalpha, IKKb or IKKepsilon. This antibody recognizes human, mouse, and rat IL-1RAcP (66 kD). No cross-reactivity with other members of the IL-1 receptor family. This antibody recognizes human, mouse, and rat IRAK-M (68 kD). No cross-reactivity with IRAK or IRAK2. This antibody recognizes human, mouse, and rat LGI1. This antibody recognizes human, mouse, and rat mGluR1 and mGluR5. This antibody recognizes human, mouse, and rat mGluR1/5. This antibody recognizes human, mouse, and rat Mitofusin-2. It does not cross- react with Mitofusin-1. This antibody recognizes human, mouse, and rat Neuroligin-1. It does not cross- react with other Neuroligins. This antibody recognizes human, mouse, and rat NR1. This antibody recognizes human, mouse, and rat NRCAM. This antibody recognizes human, mouse, and rat PCDHG-A, B, and C proteins This antibody recognizes human, mouse, and rat Piccolo isoforms (other species not tested). It does not cross-react with Bassoon. This antibody recognizes human, mouse, and rat PINK1. This antibody recognizes human, mouse, and rat PTPRF. This antibody recognizes human, mouse, and rat QKI-5. It cross-reacts with QKI-6, QKI-7, and QKI-7b. This antibody recognizes human, mouse, and rat Shank 1, 2, and 3. This antibody recognizes human, mouse, and rat Shank 1. It does not react with Shank2 or 3. This antibody recognizes human, mouse, and rat SHANK1/SHANK3. This antibody recognizes human, mouse, and rat Shank3. It does not cross-react with Shank1 or Shank2. This antibody recognizes human, mouse, and rat SNAT1. This antibody recognizes human, mouse, and rat VAChT. This antibody recognizes human, mouse, and rat VGlut1. It does not cross-react with VGlut2. This antibody recognizes human, mouse, and rat VGlut2. This antibody recognizes human, mouse, and rat VGlut3. It does not cross-react with VGlut1 or VGlut2. This antibody recognizes human, mouse, rat, bovine, and monkey Rab5. Other species have not been tested. This antibody recognizes human, mouse, rat, bovine, canine, chicken, guinea pig, monkey, pig, hamster, rabbit, and sheep calreticulin. This antibody recognizes human, mouse, rat, bovine, chicken, dog, guinea pig, hamster, pig, monkey, rabbit, and sheep calnexin. This antibody recognizes human, mouse, rat, bovine, chicken, sheep, Drosophila, and Xenopus ERK1/2. This antibody recognizes human, neurturin (14 kD). This antibody recognizes mouse and rat Brevican. This antibody recognizes mouse and rat Delta GABA-A receptor. This antibody recognizes mouse and rat GluA1/GluR1. It does not cross-react with GluR2. This antibody recognizes mouse and rat LRP4. This antibody recognizes mouse and rat Notch1. It does not cross-react with Notch2 or Notch3. This antibody recognizes mouse and rat Synaptotagmin-7. It does not cross- react with other Synaptotagmins. This antibody recognizes mouse and rat Versican. This antibody recognizes mouse Kos1 protein. This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins. This antibody recognizes mouse PAPK. Sequence homology with human PAPK is 60%. This antibody recognizes mouse, rat, and bovine PSD95. This antibody recognizes mouse, rat, pig, and human PSD95. This antibody recognizes native and human and mouse CLAC-P. This antibody recognizes proteins containing acetylated lysine residues. It does not react with non-acetylated lysine residues. This antibody recognizes proteins containing acetylated lysine residues. It does not recognize non-acetylated proteins. This antibody recognizes proteins containing methylated lysine residues. It does not recognize non-methylated proteins. This antibody recognizes Rattin (rat). This antibody recognizes the C-terminal aa TETSQVAPA(COOH) of native and recombinant vertebrate rhodopsin. This antibody recognizes the GABABR1 subunit. The GABAB receptor is the first discovered G-protein-coupled receptor whose function requires two subunits, R1 and R2, to form a functional receptor. The This antibody recognizes the human and rat GABABR2 subunit. This antibody recognizes the human variant of neuronal nitric oxide synthase (nNOS). nNOS is one of three NOS isoforms along with endothelial cell NOS (eNOS) and inducible NOS (iNOS). The three isofo This antibody recognizes the N-terminus of Rhodopsin from all mammalian species tested (human, mouse, rat, bovine, porcine), and most fish, birds, and amphibians. This antibody recognizes the phosphorylated and non-phosphorylated forms of mouse, rat, and bovine CaMKII. This antibody recognizes the phosphorylated form of mouse and rat CaMKII. It does not react with non- phosphorylated CaMKII. This antibody specifically recognizes an epitope within Abx-40. NOTE: When administered to young Tg2576 mice with minimal Ab deposition, this antibody reduced Ab accumulation in the brain. This antibody specifically recognizes an epitope within Abx-42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition, this antibody reduced Ab accumulation in the brain. This antibody specifically recognizes an epitope within domain III of human calpastatin. This antibody specifically recognizes human IRAK-4 (IL-1 Receptor Associated Kinase-4). This antibody does not cross-react with other IRAKs. Binds multiple linear epitopes within human alpha synuclein: 21-70 aa, 61-90 aa, and 101-140 aa, determined using Dot blot and ELISA with corresponding peptides. Detects ~14 kDa band corresponding to Binds within the 101-130 aa region of human alpha synuclein, determined using Dot blot and ELISA with corresponding peptides. Detects ~14 kDa band corresponding to Alpha synuclein. Band at ~40 kDa is Binds within the 101-140 aa region of human alpha synuclein, determined using WB and ELISA with corresponding peptides. Detects ~14 kDa band corresponding to Alpha synuclein. Does not detect truncat Binds within the 81-130 aa region of human alpha synuclein, determined using WB and ELISA with corresponding peptides. Detects ~14 kDa band corresponding to Alpha synuclein. Band at ~30 kDa is a dime Detects ~140kDa. Weak human detection. Does not cross-react with KCNT2/Slo2.1/Slick. Specific for Acrolein modified proteins. Does not detect free acrolein. Does not cross-react with Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, Malondialdehyde, or Methylgl Specific for Malondialdehyde conjugated proteins. Does not detect free Malondialdehyde. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, or This antibody reacts with cyclic AMP and to lesser degrees with other 5' nucleotides. This antibodyThis antibody recognizes a unique epitope within the immunoglobulin (Ig)-like domain of arginine-gingipain (RgpB). recognizes NMDAR subunits NR3A and NR3B. It does not cross-react with
