TRAP1/Hsp75 Monoclonal Antibody
Catalog No.: 11143 (clone 3H4-2H6)
Size: 100ug in PBS (1mg/ml), pH 7.4, 50% glycerol, 0.09% sodium azide.
Purified by Protein G affinity chromatography.
The molecular chaperone family of 90kDa heat shock proteins (Hsp90) is a highly conserved protein family that plays an important physiological role. Hsp90 is best known for its association with signal transduction processes. Tumor necrosis factor receptor-associated protein 1 (TRAP1) is a recently cloned homolog of Hsp90. Like Hsp90, TRAP1 is associated with numerous proteins that are involved in multiple pathways. Data indicates that TRAP1 is a mitochondrial matrix protein: it is localized in mitochondria of mammalian cells and contains a mitochondrial targeting presequence.
Antigen: Recombinant human TRAP1
Accession no.: NP_057376.2
Gene ID: 10131
Host Species: Mouse
Antibody Class: IgG1
This antibody recognizes human and rat TRAP1. Other species have not been investigated.
Immunoblotting: use at 1ug/ml. A band of ~75kDa is detected.
Positive control: A431 cell lysate or rat brain lysate.
These are recommended concentrations; enduser should determine optimal concentrations for their applications.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze- thaw cycles.
For in vitro investigational use only. Not intended for diagnostic or therapeutic applications.