Anti-TRAIL (CT) Antibody
Catalog No.: 2430
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain-containing receptors, TNFR1 and Fas. A novel member of the TNF family has been identified and designated TRAIL (TNF- related apoptosis-inducing ligand) and Apo- 2L (Apo-2 ligand). TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain-containing receptors, DR4 and DR5, have been identified as the receptor for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF- B activation in many tissues and cell types.
Antigen: Synthetic peptide corresponding to aa 261-277 of human TRAIL (accession no. NP_003801).
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes human TRAIL.
Immunoblotting: use at 1ug/ml.
Positive control: HeLa cell lysate.
Immunocytochemistry: use at 20ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their application.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.