Toll-like Receptor 6 (TLR6) Polyclonal Antibody
Catalog No.: 56506
Size: 50ug purified by antigen affinity chromatography in PBS containing 0.02% sodium azide.
TLR6 is a 796 aa protein containing 20 N- terminal leucine-rich repeat motifs (LRRs) with a molecular weight of 91 kDa. TLR6 is most closely related to TLR1, TLR10, and TLR2 with 68%, 46%, and 31% overall aa sequence identity, respectively. In vivo, TLR6 transcript is observed in thymus, spleen, and lung. TLR6 mRNA expression is highest in B cells and monocytes. TLR6 forms a heterodimer with TLR2. Like TLR1, TLR6 is thought to specify or enhance TLR2 and contribute to its signaling capabilities through heterodimerization.
Antigen: Synthetic peptide corresponding to 13 amino acids near the center of human TLR6.
Host Species: Rabbit
Antibody Class: Polyclonal
Preservatives: 0.02% sodium azide
This antibody recognizes human TLR6.
Western blotting: use at 0.5-1ug/ml. A band of approximately 91 kDa is detected.
Immunohistochemistry: formalin-fixed, paraffin-embedded tissues, use at 5ug/ml.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
Store at 4°C (short-term) or -70°C (long- term).
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.