Telomerase-Associated Protein-1 Polyclonal Antibody
Catalog No.: 34026
Size: 50ug immunogen affinity purified antibody in PBS containing 0.02% sodium azide.
Telomerase is a reverse transcriptase that adds telomeric repeats (TTAGGG) to chromosome ends. In normal somatic cells, telomerase is not active and telomeres progressively shorten, leading to limited cell lifespan and senescence. Activation of telomerase is associated with human cancers and cell immortalization. Human telomerase is comprised of three major subnunits: a catalytic subunit (hTERT), a template RNA (hTR), and telomerase-associated protein (TEP-1). Transcription of TERT is the primary mechanism for regulating telomerase activity.
Antigen: Synthetic peptide conjugated to KLH
Host Species: Rabbit
Preservatives: 0.02% sodium azide
This antibody recognizes an epitope within 20 amino acids near the amino terminus of human TEP-1.
Immunoblotting: Use at 5ug/ml.
Immunohistochemistry: Use at 5ug/ml.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable at 4°C (short- term) and -70°C (long-term).
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.