Anti-Survivin (NT) Antibody
Catalog No.: 2233
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Apoptosis can be prevented by the inhibitor of apoptosis proteins (IAPs). IAPs constitute a conserved gene family that binds to and inhibits cell death proteases. A novel IAP has been identified and designated Survivin. Survivin interacts with the processed form of caspase-3 and inhibits its proteolytic activity. Survivin is expressed predominantly in tissues of embryos, transformed cell lines, and many human cancers.
Antigen: Synthetic peptide corresponding to aa 1-12 of human Survivin (accession no. NP_001159).
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes human Survivin (17kDa).
Immunoblotting: use at 1ug/ml.
Positive control: MOLT4 cell lysate.
Immunocytochemistry: use at 5ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.