SMRT Monoclonal Antibody
Catalog No.: 56217
Size: 100 ug in 10 mM PBS, pH 7.4.
SMRT (Silencing Mediator for Retinoid and Thyroid receptors) is a 168 kD nuclear protein. Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand, there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.
Antigen: A KLH-conjugated synthetic peptide derived from human SMRT corresponding to aa 994-1005
Host Species: Mouse
Preservatives: None. Available on request.
This antibody recognizes human SMRT.
Immunoblotting and Immunoprecipitation: use at 1-5 ug/ml.
Positive control: HBL100
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.