Catalog No.: 34009
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma-tography.
A novel gene containing SNF2, PHD- finger, RING-finger, helicase, and linker histone domains termed SHPRH, is a possible candidate for a tumor suppressor gene. These domains are characteristic of several DNA repair proteins, transcription factors, and helicases. Mapping of this gene to 6q24, a region reported to contain a tumor suppressor locus, suggests a role for SHPRH in tumor suppression.
Immunogen: Synthetic peptide corresponding to aa residues 515-535 (DKTKKQAVGSPRKIEKELRKS) of mouse SHPRH conjugated to KLH at the N-terminus.
Host Species: Rabbit
Preservatives: None. Available on request.
This antibody recognizes mouse SHPRH (approx. 185 kDa) which has 90% sequence homology with human and 95% sequence homology with rat.
Immunoblotting : use at 1:250 dilution.
Positive control: Mouse brain lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Sood R. et al. (2003) Genomics 82:153-161.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.