Recombinant Human Hsp22

Recombinant Human Hsp22

ORDERING INFORMATION

Formulation: White powder lyophilized from a 1mg/ml sterile-filtered solution in 20mM Tris-acetate buffer, pH 7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF, and 15mM β-mercaptoethanol. Purified by proprietary chromatographic techniques.

BACKGROUND

Hsp22, a Mn+2-dependent serine- threonine-specific protein kinase displays temperature-dependent chaperone activity. Defects in Hsp22 cause distal hereditary motor neuropathy type 2 (also known as distal spinal muscular atrophy) and spinal muscular atrophy of the charcot-marie- tooth type.

SPECIFICATION SUMMARY

Source: Escherichia coli Purity: Greater than 95% as determined by SDS-PAGE. Accession number: Q9UJY1
Solubility: Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed.

STORAGE AND STABILITY

Store at or below -20°C. After reconstitution, store at 4°C for up to one week and at or below -20°C for future use. Addition of a carrier protein (such as 0.1% HSA or BSA) is recommended for long-term storage.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.