Recombinant Human Cardiac Troponin I-C Complex

Recombinant Human Cardiac Troponin C (TnC)

ORDERING INFORMATION

Format: 0.5mg/ml sterile-filtered solution with 50% glycerol. Purified subunits of recombinant Troponin I, Troponin C, and Troponin T are complexed in vitro under appropriate conditions.

BACKGROUND

Troponin Complex is a heteromeric protein complex comprised of Troponin I, Troponin T, and Troponin C subunits that function in the regulation of skeletal and cardiac muscle contraction. Each subunit has a unique function; Troponin T binds the troponin components to tropomyosin, troponin I inhibits the interaction of myosin with actin, and troponin C contains the binding sites for Ca²⁺ that helps initiate contraction. Troponin is the current biomarker of choice for the detection of cardiac injury.

DESCRIPTION

Source: Recombinant human Cardiac Troponins I, T, and C are produced in E. coli.
Purity: Greater than 90% as determined by RP-HPLC and SDS-PAGE.
Carrier Protein: None.

STORAGE AND STABILITY

Store at 4°C if entire quantity of product will be used within 2-4 weeks or at -20°C long-term in appropriate aliquots to avoid multiple freeze-thaw cycles.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.