Recombinant Human Annexin A7

$3,740.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
	1000ug	WB	Human

SKU: 13822P-1000 Categories: Products, Recombinant Proteins

Overview

Product Name Annexin A7 (13822P-1000)

Description Recombinant Human Annexin A7 produced in E. coli is a single, non- glycosylated polypeptide containing amino acids 1-466 with a molecular weight of 52.9kDa. It includes a 24 amino acid His-tag at the N-terminus.

Target Annexin A7

Product Background Annexin 7 is a member of the annexin family of calcium-dependent phospholipids binding proteins. It includes a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter is composed of alternating hydrophobic and hydrophilic segments. Analysis of this protein suggests that Annexin 7 is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity, and membrane fusion.

Species Reactivity Human

Applications WB

Source Escherichia coli

Properties

Form Liquid

Concentration Lot Specific

Formulation Sterile-filtered clear solution (0.25mg/ml) in 20mM Tris-HCl, pH 8.0, 150mM NaCl,1mM DTT, 40% glycerol.

Buffer Formulation 20 mM Tris

Buffer pH pH 8.0

Buffer Cryopreservative 40% glycerol

Purity Greater than 85% as determined by SDS-PAGE

Target Name Annexin A7

Target ID Annexin A7

Alternative Names Annexin A7

Sequence MGSSHHHHHH SSGLVPRGSH

Biological Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

Background Annexin 7 is a member of the annexin family of calcium-dependent phospholipids binding proteins. It includes a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter is composed of alternating hydrophobic and hydrophilic segments. Analysis of this protein suggests that Annexin 7 is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity, and membrane fusion.

Handling

Storage Store at 2 - 8ºC. Do not Freeze.

Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.

Data Sheet