Recombinant Human Alpha Crystallin B (CRYAB)

$173.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
	20ug	WB	Human

SKU: 11073P-20 Categories: Products, Recombinant Proteins

Overview

Product Name Alpha Crystallin B (11073P-20)

Description Recombinant Human CRYAB produced in E. coli is a single, non-glycosylated polypeptide chain containing 175 amino acids with a molecular weight of 20.2kDa.

Target Alpha Crystallin B

Product Background Alpha crystallins are composed of two gene products: alpha-A (acidic) and alpha-B (basic). Alpha crystallins are induced by heat shock and are members of the small heat shock protein family. They act as molecular chaperones. In addition, alpha crystallins have autokinase activity and play a role in intracellular architecture. Alpha crystalline B is expressed in many tissues and is associated with many neurological diseases.

Species Reactivity Human

Applications WB

Source Escherichia coli

Properties

Form Liquid

Concentration Lot Specific

Formulation Sterile-filtered colorless solution contains 20mM Tris-HCl, pH 7.5, 50mM NaCl and 1mM EDTA.

Buffer Formulation 20 mM Tris

Buffer pH pH 7.5

Purity Greater than 95% as determined by SDS-PAGE and RP- HPLC

Target Name Alpha Crystallin B

Target ID Alpha Crystallin B

Alternative Names CRYAB

Sequence MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSWFDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHRKYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK

Background Alpha crystallins are composed of two gene products: alpha-A (acidic) and alpha-B (basic). Alpha crystallins are induced by heat shock and are members of the small heat shock protein family. They act as molecular chaperones. In addition, alpha crystallins have autokinase activity and play a role in intracellular architecture. Alpha crystalline B is expressed in many tissues and is associated with many neurological diseases.

Handling

Storage Store at 2 - 8ºC. Do not Freeze.

Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.

Data Sheet