PSAP

PSAP Monoclonal Antibody

ORDERING INFORMATION

Format: Purified antibody in Tris buffer, pH 7.3-7.7, 1% BSA, <0.1% sodium azide.

BACKGROUND

Prostatic Specific Acid Phosphatase (PSAP) is an enzyme found in the glandular epithelium of the prostate. PSAP levels are elevated in hyperplastic prostate and prostate carcinoma with the highest levels being detected in metastasized prostate cancer. Moderate overexpression of PSAP is also characteristic of diseases of the bone (such as Paget’s disease or hyperparathyroidism), diseases of blood cells (such as sickle-cell disease), multiple myeloma, or lysosomal storage diseases such as Gaucher’s disease.

DESCRIPTION

Antigen: Recombinant human PSAP.
Accession No.: P15309
Host: Mouse
Antibody Subtype: IgG1
Specificity: Human PSAP. Reactivity with other species has not been investigated.

APPLICATIONS

Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.

STORAGE AND STABILITY

Store at 2-8°C. Do not freeze.

For in vitro investigational use only. Not for use in diagnostic or therapeutic applications.