Anti-PSA Antibody (34069)

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ul IHC Human
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Overview
Product Name Anti-PSA Antibody (34069)
Description Anti-PSA Mouse Monoclonal Antibody
Target PSA
Species Reactivity Human
Applications IHC
Host Mouse
Clonality Monoclonal
Clone ID G654.1
Isotype IgG1
Immunogen Recombinant human PSA.
Properties
Form Liquid
Concentration Lot Specific
Formulation Tris buffer, pH 7.3-7.7, 1% BSA, 0.1% sodium azide.
Buffer Formulation Tris
Buffer pH pH 7.3-7.7
Buffer Anti-Microbial 0.1% Sodium Azide
Buffer Protein Stabilizer 1% Bovine Serum Albumin
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity Human PSA. Reactivity with other species has not been investigated.
Target Name Prostate-specific antigen
Target ID PSA
Uniprot ID P07288
Alternative Names PSA, EC 3.4.21.77, γ-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase
Gene Name KLK3
Sequence Location Secreted.
Biological Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Research Areas Cancer research
Background Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein- related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is present in small quantities in the serum of men with healthy prostates but is often elevated in cases of prostate cancer or other prostate disorders.
Application Images
Description Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes. Detection of PSA in human prostate with #34069 diluted 1:100-1:200.
Additional Information
Handling
Storage Store at 2-8°C. Do not freeze.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions

Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.
References & Data Sheet