Progesterone Receptor Monoclonal Antibody
Catalog No.: 3341
Size: 100 ug Protein G-purified antibody in PBS, pH 7.4
Antigen: 6-His fusion protein containing the region encoding aa 1-101 of human progesterone receptor expressed in E. coli.
Host Species: Mouse
Antibody Class: IgG2a/κ
Preservatives: None. Available on request.
This antibody recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.
Immunoblotting: use at 1-5 ug/ml.
Positive controls: MCF7 cells or recombinant protein.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.