Procainamide Monoclonal Antibodies
ORDERING INFORMATION
Catalog No. 16701 |
Clone No. PC10-138.2 |
MAb Subtype IgG3* |
Size 100ug, 500ug |
Library Pack No. 167101 |
100ug/clone All 7 clones |
16704 |
PC12-416.1.1 |
IgG2b |
100ug, 500ug |
||
16705 |
PC12-424.5 |
IgG2b |
100ug, 500ug |
||
16706 |
PC10-131.1 |
IgG2b |
100ug, 500ug |
||
16707 |
PC10-183.2 |
IgG2a |
100ug, 500ug |
||
16708 |
PC10-242.6 |
IgG2b |
100ug, 500ug |
||
16709 |
PC10-253.2 |
IgG3* |
100ug, 500ug |
Format: Protein G-purified antibody in PBS, pH 7.4. *PEG-purified antibody in PBS, pH 7.4
BACKGROUND
Procainamide is an antiarrhythmic used to treat cardiac arrhythmias. It induces rapid block of the batrachotoxin (BTX)-activated sodium channels of the heart muscle and acts as antagonist to long gating closures. Procainamide is metabolized via different pathways. The most common one is the acetylation of procainamide to the less toxic N- acetylprocainamide. Procainamide was approved by the US FDA on June 2, 1950.
SPECIFICATION SUMMARY
Antigen: Procainamide conjugated to KLH by proprietary chemistry.
Host Species: Mouse
Specificity: These antibodies recognize procainamide and cross-react to different degrees with N-Acetylprocainamide:
% Cross-Reactivity with N-Acetylprocainamide | |
16701 |
8.4 |
16704 |
11.3 |
16705 |
10.6 |
16706 |
3.2 |
16707 |
0.4 |
16708 |
11.1 |
16709 |
2.2 |
APPLICATIONS
These antibodies have been qualified for use in ELISA to detect procainamide.
DILUTION INSTRUCTIONS
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not intended for use in therapeutic or diagnostic procedures.
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