Phytanoyl-CoA 2-hydroxylase (PHYH / PAHX) Monoclonal Antibody
Catalog no.: 13825 (clone S210-5)
Format: 100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
The PHYH gene codes for the enzyme phytanoyl-CoA 2-hydroxylase which is critical for the normal function of peroxisomes. One substance broken down in peroxisomes is phytanic acid, a type of fatty acid obtained primarily from beef and dairy products. Phytanoyl-CoA 2-hydroxylase is responsible for one of the first steps in breaking down phytanic acid via alpha-oxidation. In subsequent steps, additional enzymes in peroxisomes and other parts of the cell further process this compound into smaller molecules that are utilized as sources of energy. Phytanoyl-CoA 2- hydroxylase may have other functions in addition to its role in breaking down phytanic acid; it appears to help determine the number of peroxisomes within cells and is involved in regulating their activity.
Antigen: Fusion protein corresponding to aa 1-338 (full-length) of human PHYH. This sequence is 78% identical in rat and 78% identical in mouse.
Accession nos: NP_001032626.1, O14832
Gene ID: 5264
Host Species: Mouse
Antibody Class: IgG1
Specificity: This antibody recognizes human, mouse, and rat PHYH.
Immunoblotting: use at 1-5ug/ml. A band of ~40kDa is detected.
Immunofluorescence: use at 10ug/ml.
These are recommended concentrations. Endusers should determine optimal concentrations for their application.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This product is stable for at least one (1) year at -20°C.
For in vitro investigational use only. Not intended for therapeutic or diagnostic procedures.