Anti-PHAP I (IN) Antibody
Catalog No.: 11082
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Antigen: Synthetic peptide corresponding to amino acids near the carboxy terminus of human PHAP I (accession no. P39687).
Host Species: Rabbit
Preservatives: 0.02% sodium azide
The PHAP proteins (tumor suppressor putative HLA-DR associated proteins) are important regulators of mitochondrial apoptosis. PHAP facilitates apoptosome- mediated caspase-9 activation to stimulate the mitochondrial apoptosis pathway. In addition, PHAP opposes both Ras- and myc- mediated cell transformation.
This antibody recognizes human and mouse PHAP I (32kDa). The sequence of rat PHAP I is identical to human PHAP I.
Immunoblotting: Use at 2-4 ug/ml.
Positive control: Raji cell lysate.
Immunocytochemistry: use at 2ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.