Anti-PAPK (ALS2CR2) Antibody
Catalog No.: 28107
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma- tography.
PAPK (polyploidy-associated protein kinase) is a new member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival. Activation of a death signal transduction pathway may result in the stimulation of the PAPK promoter which leads to increased PAPK expression and provides a negative feedback signal that prevents cell death. Another name for this protein is ALS2CR2 (amyotrophic lateral sclerosis 2 chromosome region candidate 2, isoform A).
Nishigaki, K et al. (2003) J Biol Chem 15: 13520-30.
Immunogen: Synthetic peptide corresponding to amino acids 399-418 (SPWSELEFQFPDDKDPVWEF) of mouse PAPK conjugated to KLH at the C-terminus.
Host Species: Rabbit
Preservatives: None. Available on request.
This antibody recognizes mouse PAPK. Sequence homology with human PAPK is 60%.
Immunoblotting: use at 1:250 dilution. A band of approximately 46-47 kDa is detected.
Positive control: liver tissue lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.