p53R2 (NT) Polyclonal Antibody
Catalog No.: 56224
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Antigen: Peptide corresponding to aa 2-17 of human p53R2.
Host Species: Rabbit
Preservatives: 0.02% sodium azide
This antibody recognizes an epitope at the N-terminus of human, mouse, and rat p53R2, a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by agents that cause DNA damage, such as UV and γ-irradiation. The product of the p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA.
Immunoblotting: use at 0.5-1 ug/ml. In immunoblots, a band of 39 kD is detected.
Positive control: A431 cell lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.