p53 Monoclonal Antibody
Catalog No.: 3339
Size: 100ul Protein G-purified antibody at 1mg/ml in PBS, pH 7.4.
Antigen: Recombinant human p53 expressed in E. coli.
Host Species: Mouse
Antibody Class: IgG2a/κ
Preservatives: None. Available on request.
This antibody recognizes an epitope within aa 20-25 at the N-terminus of human p53. p53 is a nuclear protein and tumor suppressor that is mutated in a wide variety of cancers. It mediates cell cycle arrest in response to DNA damage, making it important in the maintenance of genomic stability.
Immunoblotting, immunoprecipitation, immunohistochemistry, and ELISA: use at 1-5 ug/ml.
Positive control: HBL 100 cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Vojtesek B. 1992. J Immunol Meth 151: 237-244.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.