Anti-p53 Monoclonal Antibody
Catalog No.: 34037 (clone PAb1801 Size: 100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide.
Purified by Protein A affinity chromatography.
p53 is a DNA-binding, cell cycle-regulating transcription factor that governs cell division. It plays a critical role in tumor suppression and has been referred to as “the guardian angel gene” or “the master watchman”. Defects in p53 are linked to >50% of human cancers and restoring p53 function to cancer cells can induce growth arrest and apoptosis. Damaged p53 can also lead to autoimmune disorders.
Antigen: Fusion protein corresponding to aa 46-53 of human p53.
Host Species: Mouse
Antibody Class: IgG1
This antibody recognizes human p53.
ELISA, Immunoblotting (1:1,000-1:2,000)
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid repeated freezing and thawing.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.