MSH6 Monoclonal Antibody
Catalog No. Clone No. Size
34076 G006.1 100ul
Format: Purified antibody in Tris buffer, pH 7.3-7.7, 1% BSA, <0.1% sodium azide.
MutS Homolog 6 (MSH6) is a protein involved in the mismatch-repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer, and mutations in this gene are correlated with the development of sporadic colorectal carcinoma. Studies have shown that mutations in MSH6, when co-indicated with mutations in MSH1 and MSH2, contribute to the development of sporadic colorectal carcinoma.
Antigen: Recombinant human MSH6.
Accession No.: P52701
Gene ID: 2956
Antibody subtype: IgG1
Specificity: Human MSH6. Reactivity with other species has not been investigated.
Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.
STORAGE AND STABILITY
Store at 2-8ºC. Do not freeze.
For in vitro investigational use only. Not for use in diagnostic or therapeutic applications.