Product Name Anti-KLK3 Antibody (56236)
Description Anti-KLK3 Rabbit Polyclonal Antibody
Species Reactivity Human
Immunogen Peptide corresponding to aa 247-261 of human KLK3 protein.
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Purification Purified by Protein A affinity chromatography
Specificity This antibody recognizes human KLK3 (prostate specific antigen, PSA), one of the many kallikrein serine proteases associated with carcinogenesis. KLK3 is a specific marker for prostate carcinoma that has also been associated with breast cancer and possibly other cancers.
Target Name Prostate-specific antigen
Target ID KLK3
Uniprot ID P07288
Alternative Names PSA, EC 126.96.36.199, γ-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase
Gene Name KLK3
Sequence Location Secreted.
Biological Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Research Areas Cancer research
Storage Store at 2 - 8ºC. Do not Freeze.
Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 30 kD is detected.