IRAK-4 Polyclonal Antibody
Catalog No.: 56412
Size: 100ug IgG (1mg/ml) in PBS, pH 7.4, purified by immunoaffinity chroma- tography.
IRAK-4 activates the NF-B and MAPK pathways and plays a role in IL-1R mediated inflammatory responses and innate immunity. IRAK-4-deficient animals are resistant to challenge with LPS and are impaired in their responses to viral and bacterial challenges.
Antigen: A synthetic peptide corresponding to amino acids at the carboxy terminus of human IRAK-4. Host Species: Rabbit Preservative: 0.02% sodium azide
This antibody specifically recognizes human IRAK-4 (IL-1 Receptor Associated Kinase-4). This antibody does not cross-react with other IRAKs.
Dilute in PBS or medium which is identical to that used in the assay system
Immunoblotting: Use at 1-4ug/ml. A band of approximately 50kDa is detected.
Immunocytochemistry: Use at 10ug/ml.
Immunofluorescence: Use at 10ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
STORAGE AND STABILITY
Stable for one year at -20C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in diagnostic or therapeutic procedures.