Catalog No.: 28106
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma- tography.
Humanin is a secreted 24-aa polypeptide that specifically protects against neuronal cell death induced by beta-amyloid peptide or by mutations causing early-onset familial Alzheimer’s disease. It does not affect cell death caused by Q79 or superoxide dismutase-1.
Immunogen: Synthetic peptide corresponding to amino acids 9-24 (LLLLTSEIDLPVKRRA) of human Humanin conjugated to KLH at the N- terminus.
Host Species: Rabbit
Preservatives: None. Available on request.
This antibody recognizes human Humanin conjugated to carrier proteins, as free polypeptide, and as a fusion protein.
Immunoblotting: use at 1:500 dilution.
Positive control: synthetic peptide or transfected cell lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Hashimoto,Y. et al. ( 2001) Proc Natl Acad Sci USA 98:6336-41.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.