Mikrogen Diagnostik recomWell HPV 16/18/45 ELISA Kit (7904)

$2,695.00

Host Quantity Applications Species Reactivity Data Sheet  
96 Tests ELISA Human papillomavirus 16/18/45
SKU: 7904 Categories: ,
Overview
Product Name Mikrogen Diagnostik recomWell HPV 16/18/45 ELISA Kit (7904)
Description Qualitative Enzyme immunoassay for detection of E7 oncoproteins from high risk (hr) Human Papillomavirus (HPV) types 16, 18 and 45 in cervical smears.

Product is intended for research use.
Target Human papillomavirus 16/18/45
Species Reactivity Human papillomavirus 16/18/45
Assay Type Sandwich ELISA
Applications ELISA
Properties
Background Human Papillomaviruses (HPV) are sexually transmitted viruses frequently occurring all over the world. Almost everyone comes into contact with at least one HP virus during the course of his/her life. In most cases, the infection heals on its own. In rare cases, chronic persistent infections can cause health problems. So far, more than 200 virus types are known of which approximately 40 affect the genitals. Some of these viruses are responsible for the formation of benign genital warts while other types, the so-called high risk types, contribute significantly to the development of cervical, anal, and penile carcinoma and cancer in the area of mouth and throat. The high risk HPV types 16 and 18 are found in 70% of cervical cancer. However, type 45 is also highly associated with risk, particularly for adenocarcinoma, a very aggressive type of cervical cancer.
Sample Type Serum, plasma, whole blood
Assay Resolution See Figure
Components
Microtiter Plate12 x 8 Wells
Positive Control1700 uL
Negative Control1700 uL
Lysis Buffer A50 mL
Lysis Buffer B50 mL
10X Wash Buffer130 mL
Biotinylated Detection Antibody12 mL
Streptavidin-HRP Conjugate12 mL
TMB Substrate12 mL
Stop Slution12 mL
Microplate Sealing Tape3 Each
Instuctions for Use1 Each
Evaluation Form1 Each
Specificity Information
Target ID Human papillomavirus 16/18/45
Research Areas Infectious Disease
Application Images
Description Possible use of recomWell HPV 16 18 45 and the relevance of E7

Due to the diagnostic significance of E7, the new recomWell HPV 16 18 45 can be utilized as a useful additional test in order to take further therapeutic or diagnostic measures.
Description Test principle and procedure.
Description Diagnostic Sensitivity, Diagnostic Specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV)

The sensitivity performance data for the corresponding disease stages were generated by the testing of hrHPV16 or hrHPV18 positive samples (as determined by HPV-NAT). The specificity of the different disease stages was defined as the quotient of negative E7 test results obtained divided by the corresponding total number of true negative (disease-"free") samples.
Additional Information
Handling
Storage Store at 2-8°C.
References & Data Sheet