Anti-CX3CR1 (EL) Antibody
Catalog No.: 2201
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma-tography.
CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 have been cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. This transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and was renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV- 1 and HIV-2 envelope fusion and virus infection, which can be inhibited by factalkine. CX3CR1 mediates leukocyte migration and adhesion and is expressed in a variety of human tissues and cell lines.
Antigen: Peptide corresponding to aa 175- 189 of human CX3CR1. The sequence is identical to that of rat CX3CR1 and differs from that of mouse CX3CR1 by one amino acid.
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes human, mouse and rat CX3CR1 (50 kD).
Immunoblotting: use at 1:500 dilution.
Positive control: Whole cell lysate of THP-1 cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures