Hepatitis B Virus Surface Antigen Monoclonal Antibodies
Catalog Nos.: 18601 and 18602
Format: 100ug Protein G-purified antibody in PBS, pH 7.4, 0.09% sodium azide
Hepatitis B virus is a double-stranded DNA virus and one of the smallest enveloped animal viruses. The virus particle consists of an outer lipid envelope and an icosahedral nucleocapsid core composed of protein. The nucleocapsid encloses the viral DNA and a DNA polymerase that has reverse transcriptase activity similar to retroviruses. Proteins in the outer envelope (surface antigen, HBsAg) are involved in viral binding and entry into susceptible cells. HBsAg detection by immunoassay is used in blood screening, to establish a diagnosis of hepatitis B infection in the clinical setting (in combination with other disease markers) and to monitor antiviral treatment.
Antigen: Recombinant HBsAg of ayw subtype.
Host Species: Mouse
Antibody Subtype: Both 18601 and 18602 are IgG1 antibodies.
Specificity: These antibodies recognize the following HBsAg subtypes: ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-, and ayw3 (Fer).
ELISA: the pair of 18601 and 18602 can be used in a sandwich ELISA to detect HBsAg.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
These antibodies may be stored at 4°C for one (1) year.
For in vitro investigational use only. Not intended for therapeutic or diagnostic applications.