GATA1 (Phospho-Ser310) Polyclonal Antibody
Catalog No.: 43042
Format: 100ul at 1.0mg/ml in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Affinity-purified on phosphopeptide; non-phosphopeptide- reactive antibodies were removed by chromatography on non-phosphorylated peptide.
GATA1 encodes a protein, GATA1, which belongs to the GATA family of transcription factors. This protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
Antigen: Peptide sequence that includes phosphorylation site of serine 310 (K-A-S(p)-G-K) derived from human GATA1 and conjugated to KLH.
Accession no.: P15976, NP_002040.1
Host Species: Rabbit
Specificity: This antibody detects endogenous human, mouse, and rat GATA1 only when phosphorylated at serine 310.
Immunoblotting: use at dilution of 1:500-1:1,000. A band of ~43kDa is detected.
Immunofluorescence: use at dilution of 1:100-1:200.
These are recommended working dilutions. Enduser should determine optimal dilutions for their applications
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Can be stored at 4°C for short-term use.
For in vitro investigational use only. Not intended for therapeutic or diagnostic applications.