FIG4 Monoclonal Antibody
Catalog no.: 56584 (clone S202-7)
Format: 100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
The protein encoded by the FIG4 gene belongs to the SAC domain-containing protein gene family. The SAC domain has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Diseases associated with FIG4 include Polymicrogyria, Bilateral Temporooccipital and Charcot-Marie-Tooth Disease, Type 4J.
Antigen: Fusion protein corresponding to aa 688-907 (C-terminus) of mouse FIG4. This sequence is 95% identical in rat and 91% identical in human.
Accession nos: NP_598760.1, Q91WF7
Gene ID: 103199
Host Species: Mouse
Antibody Class: IgG1
Specificity: This antibody recognizes human, mouse, and rat FIG4.
Immunoblotting: use at 1-5ug/ml. A band of ~100kDa is detected.
Immunofluorescence: use at 10ug/ml.
These are recommended concentrations. Endusers should determine optimal concentrations for their application.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This product is stable for at least one (1) year at -20°C.
For in vitro investigational use only. Not intended for therapeutic or diagnostic procedures.