FGF Receptor 1 Monoclonal Antibodies
Catalog No.: 30101 (M19B2)
Size: 250 ug Protein G-purified antibody in PBS, pH 7.4
Antigen: Recombinant human ectodomain of FGFr1β expressed in E. coli beginning with proline 23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH- terminal glu-phe sequences.
Host Species: Mouse
Antibody Class: IgG1
Preservatives: None. Available on request.
30101 reacts with both α and β isoforms. Epitope is within the NH2-terminus of Ig loop II sequence lys145 and glu159 between the acidic box and heparin-binding sequence of FGFr1.
Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1.
Immunoprecipitation: native, recombinant, and ligand-labeled FGFr1.
Immunohistochemistry: paraformalde-hyde fixed cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Xu et al. (1992) J Biol Chem 267: 17792;
Kan et al. (1993) Science 259: 1918;
Feng et al. (1996) Biochim Biophys Acta 1310: 67.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.