FGF Receptor 1α Monoclonal Antibodies
Catalog No.: 30104 (M2F12)
Size: 250 ug Protein G-purified antibody in PBS, pH 7.4
Antigen: Recombinant human ectodomain of FGFr1α expressed in E. coli beginning with pro23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH- terminal glu-phe sequences.
Host Species: Mouse
Antibody Class: IgG2a
Preservatives: None. Available on request.
30104 reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1α. Reacts with human, rat, and mouse receptor. Other species untested.
Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1.
Immunoprecipitation: native, nuclear, recombinant, and ligand-labeled FGFr1.
Immunohistochemistry: frozen sections of human glioblastomas, para-formaldehyde- fixed cells and nuclei, human myocardial biopsies.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Xu et al. (1992) J Biol Chem 267: 17792;
Proudovsky et al. (1994) J Biol Chem 269: 31720;
Morrison et al. (1994) Cancer Res 54: 2794;
Zhao et al. (1994) J Clin Invest 94: 992;
Feng et al. (1996) Biochim Biophys Acta 1310: 67.
For research only. Not for use in therapeutic or diagnostic procedures