Anti-FBG3 (F Box 3) Antibody
Catalog No.: 28104
Size: 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chroma- tography.
F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F- box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
Immunogen: Synthetic peptide corresponding to amino acids 103-119 (EWKVEDLSRDQRKEFPN) of human
FBG3 conjugated to KLH at the N- terminus.
Host Species: Rabbit
Preservatives: None. Available on request.
This antibody recognizes human FBG3 . Sequence homology to mouse and rat FBG3 is 94%.
Immunoblotting : use at 1:500 dilution. A band of approximately 31 kDa is detected.
Positive control: recombinant human FBG3.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Ilyin,GP et al. (2002) Gene 296:11-20.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.