Anti-Factor VIII Antibody (10104)

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ug
1mg
500ug 		WB,ELISA Human
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SKU: 10104 Categories: , , ,
Overview
Product Name Anti-Factor VIII Antibody (10104)
Description Anti-Factor VIII Mouse Monoclonal Antibody
Target Factor VIII
Species Reactivity Human
Applications WB,ELISA
Host Mouse
Clonality Monoclonal
Clone ID F827.4
Isotype IgG2a
Immunogen Purified human Factor VIII.
Associated Products This antibody is included in the following Library Pack containing multiple antibodies:

101101 - Anti-Factor VIII Mouse Monoclonal Antibody - Library Pack

This antibody is associated to the following antibodies of similar specification:

10101 - Anti-Factor VIII Antibody - Clone F82.2.9 - Isotype IgG1
10102 - Anti-Factor VIII Antibody - Clone F82.2.32 - Isotype IgG1
10103 - Anti-Factor VIII Antibody - Clone F85.5.72 - Isotype IgG1
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by protein G affinity chromatography
Specificity Information
Target Name Coagulation factor VIII
Target ID Factor VIII
Uniprot ID P00451
Alternative Names Antihemophilic factor, AHF, Procoagulant component [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]
Gene Name F8
Sequence Location Secreted, extracellular space.
Biological Function Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.
Research Areas Coagulation factors.
Application Images
Description Detection of Factor VIII light chain (LCh) in wild-type (WT) and recombinant (R372H) Factor VIII after reaction with thrombin over time (Nogami et al. 2005 Blood 105: 4362-4368).
Additional Information
Handling
Storage These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.
Application Instructions These antibodies have been qualified for use in ELISA and immunoblotting to detect human Factor VIII.
References & Data Sheet