Anti-Daxx (CT) Antibody
Catalog No.: 2411
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
A novel Fas binding protein was recently cloned from human and mouse and designated Daxx. Daxx binds specifically to the Fas death domain, enhances Fas induced apoptosis, and activates the Jun N- terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues, indicating its important function in Fas signaling pathways.
Antigen: Peptide corresponding to aa 722- 740 at the C-terminus of human Daxx (accession no. CAG33366).
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes full-length human, monkey, and mouse Daxx (120kDa).
Immunoblotting: use at 1:500-1:1,000 dilution.
Immunocytochemistry: use at 10ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
Positive control: Whole cell lysate from HeLa cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.